Common side effects of MDMA include loss of appetite, visual distortions, nystagmus (involuntary eye movement), increased heart rate and blood pressure, edginess, body temperature changes, vomiting, anxiety, perspiration, motion sickness, confusion, dry mouth, jaw tension, and difficulty concentrating. However, not all of these effects occur in everyone, and the dose and frequency are determining factors. Some individuals may be more prone to these negative effects than others.

Hyperthermia is a severe but rare side effect that is more likely to occur in crowded spaces, during intense physical activity such as dancing, and when proper hydration is not maintained. To prevent this, it’s recommended to take breaks from dancing, replenish fluids (with water, juice, or isotonic beverages, in moderation, about half a liter per hour for intense physical activity and less for rest), and avoid or limit alcohol, as it increases dehydration and body heat. Moderation and common sense should guide fluid intake, rather than counting exact amounts.

MDMA increases heart rate and blood pressure, so those with heart conditions or hypertension should exercise caution when using it. High and continuous doses of MDMA in frequent users can lead to memory loss and mood alterations in the future. The rule of thumb for MDMA use is «Less is more.» Bad side effects and long-term consequences decrease, and the experience becomes more enjoyable, if there is more time between doses. It is estimated that using MDMA more than once a month can be excessive. Moderating its use is the key to fully experiencing its effects and preventing long-term consequences.

It’s impossible to know a pill’s concentration of MDMA without laboratory analysis. Reagent kits are available to detect the most common adulterant