MDMA adverse effects

MDMA adverse effects

I’m still relatively new to MDMA.. well, I shouldn’t say MDMA – I should say Party Pills as I guess I really don’t know what I’m taking (I’m buying a test kit soon).I love taking party pills because it’s much better to spend $50 – $75 (on pills) on a night out rather than $200 – $300 (on alcohol). But, my only worry is health risks. The only health risks I know about are, anxiety/paranoia from taking too much (only happened once to me), and over heating – which I avoid by drinking water every 1-2 hours. Is there any other health risks that I should be worried about?  I guess you could say memory loss, but I have much more memory loss when drinking alcohol.

Originally posted in SR2.0 Forum 3/2/14 Updated 2/2/23

Common side effects of MDMA include loss of appetite, visual distortions, nystagmus (involuntary eye movement), increased heart rate and blood pressure, edginess, body temperature changes, vomiting, anxiety, perspiration, motion sickness, confusion, dry mouth, jaw tension, and difficulty concentrating. However, not all of these effects occur in everyone, and the dose and frequency are determining factors. Some individuals may be more prone to these negative effects than others.

Hyperthermia is a severe but rare side effect that is more likely to occur in crowded spaces, during intense physical activity such as dancing, and when proper hydration is not maintained. To prevent this, it’s recommended to take breaks from dancing, replenish fluids (with water, juice, or isotonic beverages, in moderation, about half a liter per hour for intense physical activity and less for rest), and avoid or limit alcohol, as it increases dehydration and body heat. Moderation and common sense should guide fluid intake, rather than counting exact amounts.

MDMA increases heart rate and blood pressure, so those with heart conditions or hypertension should exercise caution when using it. High and continuous doses of MDMA in frequent users can lead to memory loss and mood alterations in the future. The rule of thumb for MDMA use is «Less is more.» Bad side effects and long-term consequences decrease, and the experience becomes more enjoyable, if there is more time between doses. It is estimated that using MDMA more than once a month can be excessive. Moderating its use is the key to fully experiencing its effects and preventing long-term consequences.

It’s impossible to know a pill’s concentration of MDMA without laboratory analysis. Reagent kits are available to detect the most common adulterant

Subuxone (naltrexone/naloxone) intravenous

Hey doc I got a question for you., How safe is it to IV suboxone??I am doing for about one year and a half very small doses, 2mg per day.I heard that its pretty bad for your health , but it keeps me off heroin and satisfies my «needlemania» Any info??? 

Originally posted in SR2.0 8/2/14, Reviewed 2/2/23

Suboxone is a medication used in the detoxification process of opiate addiction. It contains two active ingredients, buprenorphine and naloxone. Buprenorphine works by interacting with opiate receptors in the brain, but differently than drugs like heroin or morphine, while naloxone is intended to counteract or eliminate the effects of buprenorphine.

According to a study published on PubMed, the intended effects of buprenorphine should be neutralized by naloxone. Although dealing with the physical withdrawal symptoms, such as «needlemania,» can be a significant challenge in stopping opioid use, the use of Suboxone may not be the most effective solution.

If you are considering stopping opioid use but you are still using needles, you may find the «Safer Drug Use: Getting Off Right: A Safety Manual for Injection Drug Users» guide provided by useful and informative. It is important to have an open and honest discussion with a healthcare professional about your individual needs and goals in the detoxification process

Alprazolam and zolpidem prescription

I have used ambien and or xanax to help me sleep for a long time, but Im wanting to stop getting it off the road and actually get prescribed from a real doctor. I know it sends red flags to a doctor when you specify what I want, but I know what works well with me, how can I approach this?

Originally posted in SR2.0 7/2/1, Reviewed 2/2/23

The use and prescription of benzodiazepines and derivatives is a complex and nuanced issue. In theory, it is the responsibility of a doctor to prescribe these medications, and they would be legally accountable for any negative consequences that may arise from their use. However, in today’s world, it is not difficult for people to obtain benzodiazepines and derivatives through various other means.

It is important to note that benzodiazepines and derivatives are not substances that should be taken casually, as they have a high potential for dependence and can cause other problems. However, there is no need to raise «red flags» or be overly concerned. The best approach is to have an open and honest conversation with a doctor about one’s specific needs and problems. If applicable, this could include discussions about sleep disorders. There may be alternative medications that are more effective, safer, and have fewer side effects than commonly used benzodiazepines like Xanax (alprazolam) or Ambien (Zolpidem).

Methamphetamine and extreme headache

I wanted some advice. I’m a regular injecting opiate user but tonight I had 70 mg of of ice IV for only the second time ever, just to try something different. I’d had my usual evening smack shots, probably around a point before I had the meth. Within a couple of minutes I had the most intense pain in my head, like a vice was on my head. It was an absolutely excruciating, unbearable pain. Then it started to wear off after half an hour until I power vomited. Now I’m well enough to write but still feel nauseous and have a painful headache.Does anybody have any ideas about what went wrong?  In another thread a respondent said that it was probably a blood clot and that i just dodged a stroke. They said to count myself extremely lucky and that i should start taking aspirin every day. They also said they were not a medical expert. I thought it time I get another opinion.

Originally posted in SR 2.0 3/6/22 . Reviewed 3/2/22

In medicine, one of the warning signs of a headache is that the patient says «it’s the worst headache I’ve ever had in my life». In this situation, it is mandatory to rule out a heart attack or cerebral haemorrhage. In your case, the history of intravenous use of methamphetamine (which is a stimulant and can increase blood pressure sharply), is one more reason to think that there may be an urgent pathology.. But a extreme headache followed by nausea and vomiting after iv stimulants can be a symptom of subarachnoid hemorrhage. You should seek immediate medical help to rule out this possibility. And taking aspirin would only aggravate this problem, if it exists.

MDMA and oxcarbazepine interaction

Is there a pharmacological interaction between MDMA and oxcarbazepine?

At 4I years old I was recently diagnosed as being bipolar. So my psychiatrist put me on Oxcarbazepine / Trileptal.My question is: How does Oxcarbazepine affect LSD, MDMA, psilocybin? is there any interaction?  And, does it make it unsafe for me to use them?

Originally posted in SR2.0 7/2/14, Reviewed 2/2/23

Oxcarbazepine is not known to have any interactions with recreational psychedelics. However, it is essential to keep in mind that people who have bipolar disorder may be more sensitive to the adverse effects of drugs like LSD, MDMA, or psilocybin. This increased sensitivity is not due to drug interactions, but rather due to the underlying condition of bipolar disorder.

Bipolar disorder can manifest itself in different ways, such as cyclical manic and depressive phases, but this may not always be the case.

During depressive phases, the use of psychedelics may worsen mood symptoms. However, it is important to note that some individuals may become more aware of their symptoms and avoid using these substances altogether.

On the other hand, during manic phases, some people may exhibit normal behavior or have hypomanic episodes, while others may display clear signs of inappropriate behavior. As a result, it is crucial to have a thorough understanding of one’s specific case of bipolar disorder before deciding to use these substances.

In the event that an individual decides to use these substances, it is essential to be in the presence of trustworthy individuals who are familiar with the individual and can provide support.

MDMA is generally considered to be more manageable for most people, as it allows for better control over thoughts, feelings, and actions. However, it is worth noting that a depressive episode 24-48 hours after use is more commonly observed with MDMA than with psychedelics.